Dr. Annick Mühlethaler-Mottet

Dr Annick Mühlethaler-Mottet, PhD, PD, is the Head of the Pediatric Hematology Oncology Laboratory of the University Hospital of Lausanne (DFME, CHUV) since August 2023. Dr Annick Mühlethaler-Mottet studied biology at the University of Geneva and received her PhD in Biology from the same university in 1998 working on the regulation of CIITA gene expression, the master controller of MHC-II gene expression, in the Laboratory of Prof. Bernard Mach (Department of Genetics and Microbiology). She completed a postdoctoral fellowship at the University of Geneva, focusing on the MHC-II regulation, before joining the Pediatric Hematology Oncology Laboratory of the CHUV in 2001 as a postdoctoral fellow. She was appointed Senior Research Fellow in 2009 and since 2015, became Principal Investigator in the Pediatric Hematology Oncology Laboratory leading a research sub-group focusing on neuroblastoma, a pediatric cancer of the sympathetic nervous system.

She has over 20 years of experience in the fields of biology and genetics of neuroblastoma. Her current research interests lie in identifying new therapeutic targets to improve treatment options by focusing on the molecular changes that drive tumor initiation, metastatic spread, and progression. She is currently acting as reviewer for national and international funding institutes. Since 2015, she has held the role of the Switzerland’s delegate of to various SIOPEN specialist committees, which conduct translational research linked to Phase III clinical trials.